Dr. Reeves, Pain Management Clinic: Real Hope with Dextrose and Platelet Prolotherapy
  • Dr. Reeves, Prolotherapy, Kansas City
    • Prolo/PIT: Brief Summary of Both
    • Comparing Prolotherapy and PIT
    • FAQ: About Prolotherapy
  • RESEARCH
    • Basic Science Dextrose >
      • Analgesia
      • Chondrogenesis
      • Tendon injection safe
      • Thickens lIgament
    • Dextrose RCTs >
      • Achilles Tendinopathy
      • Ankle Osteoarthritis
      • Chondromalacia patella
      • Fibromyalgia
      • Hand Osteoarthritis
      • Hip Osteoarthritis
      • Knee Osteoarthritis
      • Lateral Epicondylosis
      • Low Back/Sacroiliac Pain
      • Osgood-Schlatter Disease
      • Plantar Fasciosis
      • Rotator Cuff Tendinopathy
      • Temporomandibular Dysfunction
    • Dextrose Non RCTs >
      • ACL Laxity
      • Groin Pain
      • Patellar Tendinosis
      • Shin Splints
    • PIT Basic Science & Mechanism
    • PIT RCTS >
      • CARPAL TUNNEL SYNDROME
      • CUBITAL TUNNEL SYNDROME
    • FINDING RESEARCH
  • TRAINING IN PROLO/PIT
  • PATIENTS
    • PRP Use
    • Stem Cell Use
    • New Patient Intake Forms
    • What to expect in more detail
    • Directions to Office
    • Fiinding a Doctor
    • When Will I Feel Better With Prolotherapy?
  • HOPE
FIBROMYALGIA 
Abd Elghany et al. published the first study using dextrose injection for PRP in 2019.  This was a treatment comparison study.  The citation is  --> Abd Elghany SE, Al Ashkar DS, El-Barbary AM, El Khouly RM, Aboelhawa MA, Nada DW, Darwish NF, Hussein MS, Ragah ES, Abo-Zaid MH, Elseoky IF, Afifi S. Regenerative injection therapy and repetitive transcranial magnetic stimulation in primary fibromyalgia treatment: A comparative study. J Back Musculoskel Rehabil 2019;32:55-62.
The link for the abstract is  below 
Link to abstract for Abd Elghany article
Here  is a summary 
•Design:  Participants were randomized  to treatment of prolotherapy three times at 2 week intervals versus repetitive transcranial magnetic stimulation  rTMS every other day for 1 month.  DPT was with 12.5% dextrose/0.3% lidocaine in each trigger point as well as tender ligament and tendinous insertion points.  Injection sites were cervical intertransverse ligaments, posterior superior trapezius, infraspinatus, common extensors, iliolumbar and SI ligament. The method was not described in enough detail to be repeatable and there were no illustrations offered to help.  This is a major weakness. 
•Candidates:   Participants met American College of Rheumatology preliminary diagnostic criteria for fibromyalgia syndrome with exclusions  for secondary fibromyalgia or systemic diseases.
•Study size:   120 female, age matched FM participants.  This was a good-sized study. 
•Bias:   There was no mention of either allocation blinding or randomization method. This is an are of high potential bias. 
•Measures:  VAS pain (0-100), tender point score (classic 18), Beck Depression Inventory (BDI), Fibromyalgia Impact Questionnaire Revised (RFIQ), and measurement of cortical auditory evoked potentials (CADPs) elicited at 1000 Hz. Assessment was at 1 month post treatment.  These were excellent and standard measures. 
•ITT versus Per Protocol:   Apparently ITT equivalent. 60 per group listed for final data analysis without dropouts mentioned.   It is unusual to not have dropout from 120 initial participants.  Without clear mention of dropouts  or the presence of a consort flow diagram this is a concern and also has to be considered a potential source of bias. 
•Other: Statistical analysis does not appear to be accurate. Specificlaly, an examination of the tables shows that the raw scores for belore, immediately after treatment, and at 1 month follow-up post treatment  are listed and no change scores.  Between group analysis based on raw score comparisons are  not accurate althhough  an examinatioof the raw scores suggests that the changes in FIQR, VAS score, and tender points would all have been significant based on the estimated chagne scores. 
•Results:  The DPT group had more severe pain at baseline.  Clinically important improvements in VAS pain, and RFIQ,  were oberved, favoring DPT.  Mean tender point decrease was significantly more in the DPT group. However, the BDI and CAEPs improved significantly more in the rTMS group 
•Limitations: Short duration of follow-up; only 1 month after last treatment (2 months after start of treatment.) There was substantial bias for this study,  and it was a  treatment comparison study rather than a controlled study. The improper statistics and limited description of treatment methods are both substantial issue although the difference between groups appears to be significant if properly done. Duye to shortcomimngs and treatment comparison deisgn, this cannot be considered more than B- evidence of benfit of potential benefit of dextrose in fibromyalgia and probably close to C level evidence.  

"Real Hope for Chronic Pain"
We use dextrose and platelet prolotherapy to eliminate the causes of chronic pain.
           The treatment is like acupuncture but with injection of a solution that heals irritable nerves, stabilizes and calms arthritic joints  and repairs/regenerates sprains and strains in your body.
Contact us today for more information.

Location

Dr. K. Dean Reeves, MD P.A.
913-362-1600
4740 El Monte Street, Roeland Park, Kansas  66205


ReevesOffice@gmail.com

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  • Dr. Reeves, Prolotherapy, Kansas City
    • Prolo/PIT: Brief Summary of Both
    • Comparing Prolotherapy and PIT
    • FAQ: About Prolotherapy
  • RESEARCH
    • Basic Science Dextrose >
      • Analgesia
      • Chondrogenesis
      • Tendon injection safe
      • Thickens lIgament
    • Dextrose RCTs >
      • Achilles Tendinopathy
      • Ankle Osteoarthritis
      • Chondromalacia patella
      • Fibromyalgia
      • Hand Osteoarthritis
      • Hip Osteoarthritis
      • Knee Osteoarthritis
      • Lateral Epicondylosis
      • Low Back/Sacroiliac Pain
      • Osgood-Schlatter Disease
      • Plantar Fasciosis
      • Rotator Cuff Tendinopathy
      • Temporomandibular Dysfunction
    • Dextrose Non RCTs >
      • ACL Laxity
      • Groin Pain
      • Patellar Tendinosis
      • Shin Splints
    • PIT Basic Science & Mechanism
    • PIT RCTS >
      • CARPAL TUNNEL SYNDROME
      • CUBITAL TUNNEL SYNDROME
    • FINDING RESEARCH
  • TRAINING IN PROLO/PIT
  • PATIENTS
    • PRP Use
    • Stem Cell Use
    • New Patient Intake Forms
    • What to expect in more detail
    • Directions to Office
    • Fiinding a Doctor
    • When Will I Feel Better With Prolotherapy?
  • HOPE