Dr. Reeves, Pain Management Clinic: Real Hope with Dextrose and Platelet Prolotherapy
  • Dr. Reeves, Prolotherapy, Kansas City
    • Prolo/PIT: Brief Summary of Both
    • Comparing Prolotherapy and PIT
    • FAQ: About Prolotherapy
  • RESEARCH
    • Basic Science Dextrose >
      • Analgesia
      • Chondrogenesis
      • Tendon injection safe
      • Thickens lIgament
    • Dextrose RCTs >
      • Achilles Tendinopathy
      • Ankle Osteoarthritis
      • Chondromalacia patella
      • Fibromyalgia
      • Hand Osteoarthritis
      • Hip Osteoarthritis
      • Knee Osteoarthritis
      • Lateral Epicondylosis
      • Low Back/Sacroiliac Pain
      • Osgood-Schlatter Disease
      • Plantar Fasciosis
      • Rotator Cuff Tendinopathy
      • Temporomandibular Dysfunction
    • Dextrose Non RCTs >
      • ACL Laxity
      • Groin Pain
      • Patellar Tendinosis
      • Shin Splints
    • PIT Basic Science & Mechanism
    • PIT RCTS >
      • CARPAL TUNNEL SYNDROME
      • CUBITAL TUNNEL SYNDROME
    • FINDING RESEARCH
  • TRAINING IN PROLO/PIT
  • PATIENTS
    • PRP Use
    • Stem Cell Use
    • New Patient Intake Forms
    • What to expect in more detail
    • Directions to Office
    • Fiinding a Doctor
    • When Will I Feel Better With Prolotherapy?
  • HOPE
Picture

Groin Pain

#1 Regenerative Injection of Elite Athletes With Career-Altering Chronic Groin Pain
Topol GA, Reeves KD: Regenerative injection of elite athletes with career-altering chronic groin pain who fail conservative treatment: a consecutive case series. Am J Phys Med Rehabil 2008;87; – .
Dr. Reeves' Notes:   Dextrose 12.5% injection returns 66/72 elite rugby and soccer players to full sport who were prevented from high level play by chronic groin pain. This was a continuation of the consecutive patient study by Topol et al in 2005 with durability of benefit confirmed by up to 6 year followup.


                                                           ABSTRACT
Objective: To obtain multisport and long-term outcome data from the use of regenerative injection therapy on career-threatened athletes.
Design: Consecutive enrollment of elite performance-limited athletes with chronic groin/abdominal pain who failed a conservative treatment trial. The treatment consisted of monthly injections of 12.5% dextrose in 0.5% lidocaine in abdominal and adductor attachments on the pubis. Injection of the nociceptive source was confirmed by repetition of resistive testing 5 mins after injection.
Results: Seventy-five athletes were enrolled. Seventy-two athletes (39 rugby, 29 soccer, and 4 other) completed the minimum two-treatment protocol. Their data revealed a mean groin pain history of 11 (3–60) mos. Average number of treatments received was 3 (1–6). Individual paired t tests for Visual Analog Scale (VAS) of pain with sport (VAS Pain) and Nirschl pain phase scale measured at 0 and an average of 26 (6–73) mos indicated VAS Pain improvement of 82% (P <10 10 ). and Nirschl pain phase scale improvement of 78% (P <10 10 ). Six athletes did not improve following regenerative injection therapy treatment, and the remaining 66 returned to unrestricted sport. Return to unrestricted sport occurred in an average of 3 (1–5) mos.
Conclusions: Athletes returned to full elite-level performance in a timely and sustainable manner after regenerative injection therapy using dextrose.




#2 Prolotherapy in Elite Male Kicking-Sport Athletes
Topol GA, Reeves KD, Hassanein K. Efficacy of Dextrose Prolotherapy in Elite Male Kicking-Sport Athletes With Chronic Groin Pain. Archives Phys Med Rehabil, 2005;86:697-702.
Dr. Reeves' Notes:  Dextrose 12.5% injection returns 22/24 elite rugby and soccer players to full sport who were prevented from high level play by chronic groin pain. This involved treatment of abdominal muscle weakness, adductor sprain and osteitis pubis.


                                                               ABSTRACT
Participants: Twenty-two rugby and 2 soccer players with chronic groin pain that prevented full sports participation and who were non-responsive both to therapy and to a graded reintroduction into sports activity.
Intervention: Monthly injection of 12.5% dextrose and 0.5% lidocaine in thigh adductor origins, suprapubic abdominal insertions, and symphysis pubis, depending on palpation tenderness. Injections were given until complete resolution of pain or lack of improvement for 2 consecutive treatments.
Main Outcome Measures: Visual analogue scale (VAS) for pain with sports and the Nirschl Pain Phase Scale (NPPS), a measure of functional impairment from pain.
Results: The final data collection point was 6-32 months after treatment (mean, 17mo). A mean of 2.8 treatments were given. The mean reduction in pain during sports , as measured by the VAS, improved from 6.3 +/- 1.4 to 1.0 +/- 2.4 (P < .001), and the mean reduction NPPS score improved from 5.3 +/- 0.7 to 0.8 +/- 1.9 (P < .001). Twenty of 24 patients had no pain and 22 of 24 were unrestricted with sports at final data collection.
Conclusions: Dextrose prolotherapy showed marked efficacy for chronic groin pain in this group of elite rugby and soccer athletes.
Authors: Gastón Andrés Topol, M.D. Physical Medicine and Rehabilitation Service Jaime Slullitel Rosario Orthopedic and Trauma Institute, Argentina. Team Physiatrist, Rosario Rugby Union, K. Dean Reeves, M.D., FAAPM&R Associate Clinical Professor, Dept of PM&R, Univ. of Kansas Medical Center, and Khatab Mohammed Hassanein, Ph.D. Professor and Chairman Department of Biometry University of Kansas Medical Center, Kansas City, Kansas.
#3  Dextrose prolotherapy versus platelet rich plasma injection for chronic groin pain.
Ozkan, O., Torgutalp, S. S., Karacoban, L., Donmez, G., & Korkusuz, F. (2020). Do pain and function improve after dextrose prolotherapy or autologous platelet-rich plasma injection in longstanding groin pain?. Montenegrin Journal of Sports Science and Medicine, 9(2), 5-12. Here is a link to the article's PDF

Link to Ozcan 2020 study PDF
Here is  a summary of that article 
•Design:  This was a retrospective cohort study.  Three weekly injection sessions were given with either 8 ml of 15% dextrose via single skin penetration and 3-4 redirections  to nearby tender areas, versus 5 ml of buffy coat PRP  in a similar method.
•Candidates:  Elite male soccer players who had anterior and medial groin pain at least 6 months, resistant to conservative treatment methods. They had a painful pubic symphysis and pubic ramus, and pain with resisted adduction. 
•Study size:  15 participants ( 9 DPT and 6 PRP ).
•Measures: VAS and Nirschl Pain Phase Scale (NPPS)  to 6 months post injection.  VAS was a standard scale.  Othere scales perferred for function but the NPPS was used before in a moderately large consecutive patient trial and has the advantage of 0 meaning no pain AND no stiffness either before or after sport.  
•ITT (intention to treat)  versus Per Protocol aanalysis:  Intention to treat analysis was used and data was obtained on all participants to 6 months.    
•Other treatments given:  No exercises during the  3 week injection period. After 3 injections all were enrolled in a 12 week progressive home exercise protocol 
•Results:   A marked improvement  resulted in  VAS pain  (87.5%  in both groups), and in NPPS (80% in DPT and 89% in PRP) with no between-group differences.
•Limitations: Retrospective design is a limitation along with a lack of description about how randomization was applied.  This would be a B- level of evidence for dextrose due to a comparative treatment desing and the blinding bias.  
•Strength:  Using the same tools as the larger (n=72) Topol et al study consecutive patient study in 2008,  (Topol GA, Reeves KD. Regenerative injection of elite athletes with career-altering chronic groin pain who fail conservative treatment: a consecutive case series. Am J Phys Med Rehabil. 2008;87(11):890-902), the outcomes were virtually identical for pain improvement (87%  Ozcan versus 82% Topol) and NPPS improvement (80% Ozcan versus 78% Topol) 

"Real Hope for Chronic Pain"
We use dextrose and platelet prolotherapy to eliminate the causes of chronic pain.
           The treatment is like acupuncture but with injection of a solution that heals irritable nerves, stabilizes and calms arthritic joints  and repairs/regenerates sprains and strains in your body.
Contact us today for more information.

Location

Dr. K. Dean Reeves, MD P.A.
913-362-1600
4740 El Monte Street, Roeland Park, Kansas  66205


ReevesOffice@gmail.com

Contact Dr. Reeves, MD

    Subscribe Today!

Submit
  • Dr. Reeves, Prolotherapy, Kansas City
    • Prolo/PIT: Brief Summary of Both
    • Comparing Prolotherapy and PIT
    • FAQ: About Prolotherapy
  • RESEARCH
    • Basic Science Dextrose >
      • Analgesia
      • Chondrogenesis
      • Tendon injection safe
      • Thickens lIgament
    • Dextrose RCTs >
      • Achilles Tendinopathy
      • Ankle Osteoarthritis
      • Chondromalacia patella
      • Fibromyalgia
      • Hand Osteoarthritis
      • Hip Osteoarthritis
      • Knee Osteoarthritis
      • Lateral Epicondylosis
      • Low Back/Sacroiliac Pain
      • Osgood-Schlatter Disease
      • Plantar Fasciosis
      • Rotator Cuff Tendinopathy
      • Temporomandibular Dysfunction
    • Dextrose Non RCTs >
      • ACL Laxity
      • Groin Pain
      • Patellar Tendinosis
      • Shin Splints
    • PIT Basic Science & Mechanism
    • PIT RCTS >
      • CARPAL TUNNEL SYNDROME
      • CUBITAL TUNNEL SYNDROME
    • FINDING RESEARCH
  • TRAINING IN PROLO/PIT
  • PATIENTS
    • PRP Use
    • Stem Cell Use
    • New Patient Intake Forms
    • What to expect in more detail
    • Directions to Office
    • Fiinding a Doctor
    • When Will I Feel Better With Prolotherapy?
  • HOPE