​Basic Science Studies 

Select the  "Basic ScienceDextrose" page above for an overview of basic science studies on prolotherapy. This lists evidence that dextrose injection causes analgesia (pain relief), chondrogenicity (cartilage cell growth), is safe with direct injection of tendons, and thickens ligaments. 

​Clinical Studies: Randomized clinical trials only

Select the "Dextrose  RCTs" (Randomized Controlled Trials) page above to see the areas for which RCTs have been published.)  Below is  a talk given in December of 2020, summarized studies published since 2018 in all areas by Dr Reeves at the American Association of Orthopedic Medicine 37th Annual Conference, given virtually

​​Perineural Injection Treatment Studies

PIT, Perineural Injection Treatment, is injection with a goal to restore normal function in nerves that cause chronic pain and degeneration. It originated with Dr. John Lyftogt in New Zealand and is widely practiced and growing quickly, with some early research completed. Click on "PIT Research" page for more information.